ARG42421
anti-CD267 / TACI antibody [1A1] (APC)
anti-CD267 / TACI antibody [1A1] (APC) for Flow cytometry and Human
概述
| 产品描述 | APC-conjugated Rat Monoclonal antibody [1A1] recognizes CD267 / TACI |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The rat monoclonal antibody 1A1 recognizes an extracellular epitope of CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 1A1 |
| 同位型 | IgG |
| 靶点名称 | CD267 / TACI |
| 抗原物种 | Human |
| 抗原 | CD267-transfected RBL cells. |
| 偶联标记 | APC |
| 別名 | Tumor necrosis factor receptor superfamily member 13B; Transmembrane activator and CAML interactor; TNFRSF14B; IGAD2; CD267; RYZN; TACI; CD antigen CD267; CVID; CVID2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O14836 Human Tumor necrosis factor receptor superfamily member 13B |
|---|---|
| 基因名称 | TNFRSF13B |
| 全名 | tumor necrosis factor receptor superfamily, member 13B |
| 背景介绍 | The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. [UniProt] |
| 细胞定位 | Membrane; Single-pass type III membrane protein. [UniProt] |
| 预测分子量 | 32 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG42421 anti-CD267 / TACI antibody [1A1] (APC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG42421 anti-CD267 / TACI antibody [1A1] (APC) at 10 µl / 100 µl of peripheral whole blood.
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ARG42421 anti-CD267 / TACI antibody [1A1] (APC) FACS image
Flow Cytometry: Human lymphocytes stained with ARG42421 anti-CD267 / TACI antibody [1A1] (APC) at 10 µl / 100 µl of peripheral whole blood and co-stained with ARG53783 anti-CD19 antibody [LT19] (PE) at 20 µl / 100 µl of peripheral whole blood.
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ARG42421 anti-CD267 / TACI antibody [1A1] (APC) FACS image
Flow Cytometry: Separation of Human CD267 positive CD19 positive lymphocytes (red-filled) from Human CD267 negative CD19 negative lymphocytes (black-dashed). Human peripheral whole blood stained with ARG42421 anti-CD267 / TACI antibody [1A1] (APC) at 10 µl / 100 µl of peripheral whole blood.
