概述

产品描述	Rabbit Polyclonal antibody recognizes CD30
反应物种	Hu
应用	IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	CD30
抗原物种	Human
抗原	Synthetic peptide derived from Human CD30.
偶联标记	Un-conjugated
別名	Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30; Ki-1; Lymphocyte activation antigen CD30; CD antigen CD30; D1S166E; CD30L receptor

应用说明

应用建议	应用 推荐稀释比 IHC-P 1:100 - 1:500 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	A431
实际分子量	~ 110 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 943 Human TNFRSF8 Swiss-port # P28908 Human Tumor necrosis factor receptor superfamily member 8
基因名称	TNFRSF8
全名	tumor necrosis factor receptor superfamily, member 8
背景介绍	CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
生物功能	CD30 is a receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898). [UniProt]
细胞定位	Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm. [UniProt]
预测分子量	64 kDa
翻译后修饰	Phosphorylated on serine and tyrosine residues. [UniProt]

检测图片 (1) Click the Picture to Zoom In