ARG45056
anti-CD321 / JAM1 antibody
anti-CD321 / JAM1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit polyclonal antibody recognizes CD321 / JAM1. |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CD321 / JAM1 |
| 抗原物种 | Human |
| 抗原 | Human JAM-A/F11R recombinant protein (a.a: S28-T294). |
| 偶联标记 | Un-conjugated |
| 別名 | F11R; F11 Receptor; PAM-1; JCAM; Junctional Adhesion Molecule 1; JAM-1; JAM-A; CD321; JAMA; JAM1; Junctional Adhesion Molecule A; Platelet Adhesion Molecule 1; Platelet F11 Receptor; CD321 Antigen; JAM; KAT |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | F11R |
| 全名 | F11 receptor |
| 背景介绍 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. [UniProt] |
| 预测分子量 | 33 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45056 anti-CD321 / JAM1 antibody IHC-P image
Immunohistochemistry: Human colonic adenocarcinoma stained with ARG45056 anti-CD321 / JAM1 antibody at 2 μg/ml dilution.
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ARG45056 anti-CD321 / JAM1 antibody WB image
Western blot: T-47D, A431 and RT4 stained with ARG45056 anti-CD321 / JAM1 antibody at 0.5 μg/ml dilution.
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ARG45056 anti-CD321 / JAM1 antibody FACS image
Flow Cytometry: Daudi stained with ARG45056 anti-CD321 / JAM1 antibody at 1 μg/1x10^6 cells dilution.
