ARG65718
anti-CD34 antibody [581]
anti-CD34 antibody [581] for CyTOF®-candidate,Flow cytometry,IHC-Frozen sections and Human,Primates
Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Pro-B Cell Marker antibody; Endothelial Cell Marker antibody; Angiogenesis Study antibody
概述
| 产品描述 | Mouse Monoclonal antibody [581] recognizes CD34 |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | CyTOF®-candidate, FACS, IHC-Fr |
| 特异性 | This antibody reacts with CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 581 |
| 同位型 | IgG1 |
| 靶点名称 | CD34 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | Hematopoietic progenitor cell antigen CD34; CD antigen CD34 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P28906 Human Hematopoietic progenitor cell antigen CD34 |
|---|---|
| 基因名称 | CD34 |
| 全名 | CD34 molecule |
| 背景介绍 | CD34 protein may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| 生物功能 | CD34 is a possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. [UniProt] |
| 产品亮点 | Related products: CD34 antibodies; CD34 ELISA Kits; CD34 Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Pro-B Cell Marker antibody; Endothelial Cell Marker antibody; Angiogenesis Study antibody |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | Highly glycosylated. Phosphorylated on serine residues by PKC. |
检测图片 (1) Click the Picture to Zoom In
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ARG65718 anti-CD34 antibody [581] FACS image
Flow Cytometry: Human peripheral blood stained with ARG65718 anti-CD34 antibody [581], followed by incubation with APC labelled Goat anti-Mouse secondary antibody. CD34+ cells (blue); Leukocytes (red).
