ARG55545

anti-CD34 antibody

anti-CD34 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Pro-B Cell Marker antibody; Endothelial Cell Marker antibody; Angiogenesis Study antibody
publication_link 参考文献1

概述

产品描述 Rabbit Polyclonal antibody recognizes CD34
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CD34
抗原物种 Human
抗原 Recombinant protein of Human CD34.
偶联标记 Un-conjugated
別名 Hematopoietic progenitor cell antigen CD34; CD antigen CD34

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 12490 Mouse CD34

GeneID: 947 Human CD34

Swiss-port # P28906 Human Hematopoietic progenitor cell antigen CD34

Swiss-port # Q64314 Mouse Hematopoietic progenitor cell antigen CD34

基因名称 CD34
全名 CD34 molecule
背景介绍 CD34 protein may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
生物功能 CD34 is a possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. [UniProt]
研究领域 Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Immune System antibody; Neuroscience antibody; Pro-B Cell Marker antibody; Endothelial Cell Marker antibody; Angiogenesis Study antibody
预测分子量 41 kDa
翻译后修饰 Highly glycosylated.
Phosphorylated on serine residues by PKC.

检测图片 (3) Click the Picture to Zoom In

  • ARG55545 anti-CD34 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human placenta tissue stained with ARG55545 anti-CD34 antibody at 1:100 dilution.

  • ARG55545 anti-CD34 antibody WB image

    Western blot: 25 µg of Mouse testis lysate stained with ARG55545 anti-CD34 antibody at 1:1000 dilution.

  • ARG55545 anti-CD34 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney tissue stained with ARG55545 anti-CD34 antibody at 1:100 dilution.

文献引用

Shigella flexneri Targets Human Colonic Goblet Cells by O Antigen Binding to Sialyl-Tn and Tn Antigens via Glycan-Glycan Interactions.

ICC/IF / Human

Elizabeth Ngoc Hoa Tran et al.
ACS Infect Dis.,  (2020)

publication_link

 

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