ARG22508
anti-CD39 antibody [A1] (PE)
anti-CD39 antibody [A1] (PE) for Flow cytometry and Human
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [A1] recognizes CD39 This antibody recognizes the human CD39 cell surface antigen, a ~70-100 kDa molecule expressed on peripheral blood B cells, T cells and monocytes, and weakly expressed by granulocytes. CD39 has intrinsic ecto-ATPase activity (Wang et al. 1996), and expression can be induced on T cells and increased on B cells, as a late activation antigen (Maliszewski et al. 1994). Mouse anti Human CD39, clone A1 has been shown to block MHC independent target cell recognition by hapten-specific CTL (Scholzen et al. 2009). |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | A1 |
| 同位型 | IgG1 |
| 靶点名称 | CD39 |
| 抗原物种 | Human |
| 抗原 | PHA activated human lymphocytes |
| 偶联标记 | PE |
| 別名 | CD39; Ecto-ATPase 1; Ecto-ATPDase 1; CD antigen CD39; NTPDase-1; ATPDase; EC 3.6.1.5; Ecto-ATP diphosphohydrolase 1; NTPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; SPG64; Ecto-apyrase; Lymphoid cell activation antigen |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10ul of the suggested working dilution to label 10^6 cells * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA and 5% Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P49961 Human Ectonucleoside triphosphate diphosphohydrolase 1 |
|---|---|
| 基因名称 | ENTPD1 |
| 全名 | ectonucleoside triphosphate diphosphohydrolase 1 |
| 背景介绍 | The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| 生物功能 | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. [UniProt] |
| 预测分子量 | ~ 70 - 100 kDa |
| 翻译后修饰 | The N-terminus is blocked. Palmitoylated in the N-terminal part. |
