ARG22496
anti-CD49a / Integrin alpha 1 antibody [TS2/7] (FITC)
anti-CD49a / Integrin alpha 1 antibody [TS2/7] (FITC) for Flow cytometry and Human
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [TS2/7] recognizes CD49a / Integrin alpha 1 This antibody recognizes the human alpha 1 integrin sub-unit, which forms the VLA-1 heterodimer in association with the beta 1 integrin. VLA-1 is a receptor for collagen and laminin, and is expressed by chronically activated T cells, melanoma cells and smooth muscle cells. |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | TS2/7 |
| 同位型 | IgG1 |
| 靶点名称 | CD49a / Integrin alpha 1 |
| 抗原物种 | Human |
| 抗原 | Human CTL line directed against HLA-DR. |
| 偶联标记 | FITC |
| 別名 | VLA-1; CD49a; Integrin alpha-1; Laminin and collagen receptor; VLA1; CD antigen CD49a; CD49 antigen-like family member A |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10ul of the suggested working dilution to label 10^6 cells in 100ul. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide and 1% BSA. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ITGA1 |
| 全名 | integrin, alpha 1 |
| 背景介绍 | This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008] |
| 生物功能 | Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. [UniProt] |
| 预测分子量 | 131 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG22496 anti-CD49a / Integrin alpha 1 antibody [TS2/7] (FITC) FACS image
Flow Cytometry: HeLa cells stained with ARG22496 anti-CD49a / Integrin alpha 1 antibody [TS2/7] (FITC).
