ARG62881
anti-CD52 antibody [HI186]
anti-CD52 antibody [HI186] for CyTOF®-candidate,Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human
Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [HI186] recognizes CD52 |
|---|---|
| 反应物种 | Hu |
| 应用 | CyTOF®-candidate, FACS, IHC-P |
| 特异性 | The clone HI186 reacts with CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract. HLDA VI; WS Code BP 523 HLDA VI; WS Code T 6T-057 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | HI186 |
| 同位型 | IgG2b |
| 靶点名称 | CD52 |
| 抗原物种 | Human |
| 抗原 | Human tonsil |
| 偶联标记 | Un-conjugated |
| 別名 | He5; CAMPATH-1 antigen; Human epididymis-specific protein 5; Cambridge pathology 1 antigen; CDw52; Epididymal secretory protein E5; CDW52; CD antigen CD52 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by protein A |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD52 |
| 全名 | CD52 molecule |
| 背景介绍 | CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis. |
| 生物功能 | May play a role in carrying and orienting carbohydrate, as well as having a more specific role. [UniProt] |
| 产品亮点 | Related products: CD52 antibodies; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies |
| 研究领域 | Immune System antibody |
| 预测分子量 | 7 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG62881 anti-CD52 antibody [HI186] FACS image
Flow Cytometry: Patient sample with Acute Lymphoblastic Leukemia (CD52 positive cALL) stained with ARG62881 anti-CD52 antibody [HI186], followed by incubation with PE-labelled secondary antibody.
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ARG62881 anti-CD52 antibody [HI186] FACS image
Flow Cytometry: Patient sample with Acute Lymphoblastic Leukemia (CD52 positive cALL) stained with ARG62881 anti-CD52 antibody [HI186], followed by incubation with PE-labelled secondary antibody.
