ARG21294
anti-CD54 / ICAM1 antibody [15.2] (APC)
anti-CD54 / ICAM1 antibody [15.2] (APC) for Blocking,Flow cytometry,ICC/IF,IHC-Frozen sections,Neutralizing,Western blot and Human,Pig
Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody
参考文献1
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody [15.2] recognizes CD54 / ICAM1 |
|---|---|
| 反应物种 | Hu, Pig |
| 应用 | BL, FACS, ICC/IF, IHC-Fr, Neut, WB |
| 特异性 | Human/Porcine CD54. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 15.2 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD54 / ICAM1 |
| 抗原物种 | Human |
| 抗原 | Rheumatoid synovial cells and human monocytes |
| 偶联标记 | APC |
| 別名 | CD54; CD antigen CD54; BB2; P3.58; Intercellular adhesion molecule 1; Major group rhinovirus receptor; ICAM-1 |
应用说明
| 应用建议 |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ICAM1 |
| 全名 | intercellular adhesion molecule 1 |
| 背景介绍 | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008] |
| 生物功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Immune System antibody; Cytotoxic T Cell Surface Study antibody |
| 预测分子量 | 58 kDa |
| 翻译后修饰 | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
检测图片 (1) Click the Picture to Zoom In
-
ARG21294 anti-CD54 / ICAM1 antibody [15.2] (APC) FACS image
Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21294 anti-CD54 / ICAM1 antibody [15.2] (APC).
文献引用
Comparison of B cells' immune response induced by PEDV virulent and attenuated strains
FACS / Pig
