ARG21387
anti-CD55 antibody [143-30] (PE-Cyanine 5)
anti-CD55 antibody [143-30] (PE-Cyanine 5) for Flow cytometry,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | PE-Cyanine 5-conjugated Mouse Monoclonal antibody [143-30] recognizes CD55 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-Fr, IHC-P, WB |
| 特异性 | Human CD55. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 143-30 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD55 |
| 抗原物种 | Human |
| 抗原 | PHA activated peripheral blood mononuclear cells |
| 偶联标记 | PE-Cyanine 5 |
| 別名 | DAF; CD antigen CD55; CROM; Complement decay-accelerating factor; CR; TC |
应用说明
| 应用建议 |
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| 应用说明 | WB: Under non-reducing condition. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS, 0.1% Sodium azide and Sucrose. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P08174 Human Complement decay-accelerating factor |
|---|---|
| 基因名称 | CD55 |
| 全名 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| 背景介绍 | This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014] |
| 生物功能 | This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. [UniProt] |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | The Ser/Thr-rich domain is heavily O-glycosylated. |
