ARG22049

anti-CD62L / L-Selectin antibody [MEL-14] (APC)

anti-CD62L / L-Selectin antibody [MEL-14] (APC) for Blocking,Flow cytometry,IHC-Frozen sections and Mouse

概述

产品描述 APC-conjugated Rat Monoclonal antibody [MEL-14] recognizes CD62L / L-Selectin
反应物种 Ms
应用 BL, FACS, IHC-Fr
特异性 Mouse CD62L
宿主 Rat
克隆 Monoclonal
克隆号 MEL-14
同位型 IgG2a, kappa
靶点名称 CD62L / L-Selectin
抗原物种 Mouse
抗原 C3H/eb cloned Mouse B cell lymphoma 38C-13
偶联标记 APC
別名 Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; CD antigen CD62L; PLNHR; LSEL; CD62L; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; LAM1; LNHR; TQ1; CD62 antigen-like family member L; gp90-MEL; Lymph node homing receptor; LYAM1; LECAM1; LEU8; LAM-1

应用说明

应用建议
应用 推荐稀释比
BLAssay-dependent
FACS< 0.1 µg/10^6 cells
IHC-FrAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 PBS, 0.1% Sodium azide and Sucrose
抗菌剂 0.1% Sodium azide
稳定剂 Sucrose
浓度 0.1 mg/ml
存放说明 Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20343 Mouse SELL

Swiss-port # P18337 Mouse L-selectin

基因名称 SELL
全名 selectin, lymphocyte
背景介绍 This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
生物功能 Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. [UniProt]
预测分子量 42 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG22049 anti-CD62L / L-Selectin antibody [MEL-14] (APC) FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG22049 anti-CD62L / L-Selectin antibody [MEL-14] (APC) and ARG20817 anti-CD3e antibody [C363.29B] (FITC).