ARG62918
anti-CD7 antibody [MEM-186]
anti-CD7 antibody [MEM-186] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [MEM-186] recognizes CD7 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, IP, WB |
| 特异性 | The clone MEM-186 reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia. HLDA VI; WS Code T 6T-015 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MEM-186 |
| 同位型 | IgG1 |
| 靶点名称 | CD7 |
| 抗原物种 | Human |
| 抗原 | Human acute myelogenous leukaemia cell line KG-1. |
| 偶联标记 | Un-conjugated |
| 別名 | TP41; Tp40; T-cell antigen CD7; CD antigen CD7; T-cell leukemia antigen; LEU-9; T-cell surface antigen Leu-9; GP40 |
应用说明
| 应用建议 |
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| 应用说明 | WB: Under non-reducing condition. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | IHC-P: Spleen |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by protein A |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD7 |
| 全名 | CD7 molecule |
| 背景介绍 | CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics. |
| 生物功能 | Not yet known. [UniProt] |
| 产品亮点 | Related products: CD7 antibodies; CD7 ELISA Kits; CD7 Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: Lymphoma |
| 研究领域 | Immune System antibody |
| 预测分子量 | 25 kDa |
