ARG53894
anti-CD7 antibody [MEM-186] (PE)
anti-CD7 antibody [MEM-186] (PE) for Flow cytometry and Human
Immune System antibody
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [MEM-186] recognizes CD7 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone MEM-186 reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia. HLDA VI; WS Code T 6T-015 |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | MEM-186 |
| 同位型 | IgG1 |
| 靶点名称 | CD7 |
| 抗原物种 | Human |
| 抗原 | Human acute myelogenous leukaemia cell line KG-1. |
| 偶联标记 | PE |
| 別名 | TP41; Tp40; T-cell antigen CD7; CD antigen CD7; T-cell leukemia antigen; LEU-9; T-cell surface antigen Leu-9; GP40 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD7 |
| 全名 | CD7 molecule |
| 背景介绍 | CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics. |
| 生物功能 | Not yet known. [UniProt] |
| 研究领域 | Immune System antibody |
| 预测分子量 | 25 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG53894 anti-CD7 antibody [MEM-186] (PE) FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG53894 anti-CD7 antibody [MEM-186] (PE).
