ARG66373
anti-CD80 antibody [16-10A1] (FITC)
anti-CD80 antibody [16-10A1] (FITC) for Flow cytometry,ICC/IF,IHC-Frozen sections and Mouse,Dog
概述
| 产品描述 | FITC-conjugated Hamster Monoclonal antibody [16-10A1] recognizes CD80 |
|---|---|
| 反应物种 | Ms, Dog |
| 应用 | FACS, ICC/IF, IHC-Fr |
| 特异性 | The antibody reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes. |
| 宿主 | Hamster |
| 克隆 | Monoclonal |
| 克隆号 | 16-10A1 |
| 同位型 | IgG2 |
| 靶点名称 | CD80 |
| 抗原物种 | Mouse |
| 抗原 | Mouse CD80-transfected CHO cell line. |
| 偶联标记 | FITC |
| 別名 | B7.1; CTLA-4 counter-receptor B7.1; CD28LG; T-lymphocyte activation antigen CD80; B7-1; CD28LG1; B7; LAB7; Activation B7-1 antigen; CD antigen CD80; BB1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS (pH 7.2), 0.09 % Sodium azide and 1 % BSA. |
| 抗菌剂 | 0.09 % Sodium azide |
| 稳定剂 | 1 % BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q00609 Mouse T-lymphocyte activation antigen CD80 |
|---|---|
| 基因名称 | CD80 |
| 全名 | CD80 molecule |
| 背景介绍 | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] |
| 生物功能 | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [UniProt] |
| 预测分子量 | 33 kDa |
