ARG23537
anti-CD80 antibody [IL-A159] (PE)
anti-CD80 antibody [IL-A159] (PE) for Flow cytometry and Bovine,Sheep
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [IL-A159] recognizes CD80. Mouse anti Bovine CD80 antibody, clone IL-A159 recognizes the bovine CD80 cell surface antigen, expressed by dendritic cells, activated macrophages and activated B cells. CD80 plays a key role in co-stimulation of T cells during the primary immune response. |
|---|---|
| 反应物种 | Bov, Sheep |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | IL-A159 |
| 同位型 | IgG1 |
| 靶点名称 | CD80 |
| 抗原物种 | Bovine |
| 偶联标记 | PE |
| 別名 | B7.1; CTLA-4 counter-receptor B7.1; CD28LG; T-lymphocyte activation antigen CD80; B7-1; CD28LG1; B7; LAB7; Activation B7-1 antigen; CD antigen CD80; BB1 |
应用说明
| 应用建议 |
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| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 1% BSA and 5% Sucrose |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CD80 |
|---|---|
| 全名 | CD80 molecule |
| 背景介绍 | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] |
| 生物功能 | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG23537 anti-CD80 antibody [IL-A159] (PE) FACS image
Flow Cytometry: Figure A. FITC conjugated Mouse anti Bovine CD62L and PE-conjugated Mouse IgG1 isotype control. Figure B. FITC conjugated Mouse anti Bovine CD62L and ARG23537 anti-CD80 antibody [IL-A159] (PE). All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23537 anti-CD80 antibody [IL-A159] (PE) FACS image
Flow Cytometry: Figure A. ARG23537 anti-CD80 antibody [IL-A159] (PE) and FITC conjugated Mouse IgG1 isotype control. Figure B. ARG23537 anti-CD80 antibody [IL-A159] (PE) and FITC conjugated Mouse anti Bovine CD62L. All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
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ARG23537 anti-CD80 antibody [IL-A159] (PE) FACS image
Flow Cytometry: Figure A. FITC conjugated Mouse anti Bovine CD14 and PE-conjugated Mouse IgG1 isotype control. Figure B. FITC conjugated Mouse anti Bovine CD14 and ARG23537 anti-CD80 antibody [IL-A159] (PE). All experiments performed on red cell lysed Bovine blood gated on mononuclear cells.
