ARG62935
anti-CD81 antibody [M38] (FITC)
anti-CD81 antibody [M38] (FITC) for Flow cytometry and Human,Cat,Rabbit
Immune System antibody; Microbiology and Infectious Disease antibody
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [M38] recognizes CD81 |
|---|---|
| 反应物种 | Hu, Cat, Rb |
| 应用 | FACS |
| 特异性 | The clone M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | M38 |
| 同位型 | IgG1 |
| 靶点名称 | CD81 |
| 抗原物种 | Human |
| 抗原 | MOLT-4 (human T-ALL cell line) |
| 偶联标记 | FITC |
| 別名 | CD antigen CD81; TAPA1; Tspan-28; S5.7; CD81 antigen; Target of the antiproliferative antibody 1; Tetraspanin-28; 26 kDa cell surface protein TAPA-1; CVID6; TSPAN28 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CD81 |
| 全名 | CD81 molecule |
| 背景介绍 | CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. |
| 生物功能 | May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV. [UniProt] |
| 产品亮点 | Related products: CD81 antibodies; Anti-Mouse IgG secondary antibodies; Related news: Tools for studying Exosomes |
| 研究领域 | Immune System antibody; Microbiology and Infectious Disease antibody |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Not glycosylated. |
检测图片 (2) Click the Picture to Zoom In
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ARG62935 anti-CD81 antibody [M38] (FITC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG62935 anti-CD81 antibody [M38] (FITC) (20 µl reagent / 100 µl of peripheral whole blood).
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ARG62935 anti-CD81 antibody [M38] (FITC) FACS image
Flow Cytometry: Separation of lymphocytes (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG62935 anti-CD81 antibody [M38] (FITC) (20 µl reagent / 100 µl of peripheral whole blood).
克隆号文献
Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.
C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells.
Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen in HTLV-1-positive T cells.
