ARG42276
anti-CD94 / KLRD1 antibody [HP-3D9] (PE)
anti-CD94 / KLRD1 antibody [HP-3D9] (PE) for Flow cytometry and Human
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [HP-3D9] recognizes CD94 / KLRD1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody HP-3D9 recognizes an extracellular epitope of CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | HP-3D9 |
| 同位型 | IgG1, kappa |
| 靶点名称 | CD94 / KLRD1 |
| 抗原物种 | Human |
| 抗原 | Cultured Human NK cells. |
| 偶联标记 | PE |
| 別名 | KP43; CD antigen CD94; CD94; Natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLRD1 |
| 全名 | killer cell lectin-like receptor subfamily D, member 1 |
| 背景介绍 | Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017] |
| 生物功能 | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt] |
| 细胞定位 | Membrane; Single-pass type II membrane protein. [UniProt] |
| 预测分子量 | 21 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG42276 anti-CD94 / KLRD1 antibody [HP-3D9] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG42276 anti-CD94 / KLRD1 antibody [HP-3D9] (PE) at 10 µl / 100 µl of peripheral whole blood.
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ARG42276 anti-CD94 / KLRD1 antibody [HP-3D9] (PE) FACS image
Flow Cytometry: Separation of Human CD94 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed). Human peripheral whole blood stained with ARG42276 anti-CD94 / KLRD1 antibody [HP-3D9] (PE) at 10 µl / 100 µl of peripheral whole blood.
