ARG41632

anti-CD97 antibody

anti-CD97 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes CD97
反应物种 Hu
应用 FACS, ICC/IF, IHC-P, IP, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CD97
抗原物种 Human
抗原 Synthetic peptide of Human CD97.
偶联标记 Un-conjugated
別名 CD97; Leukocyte antigen CD97; CD97 antigen; CD antigen CD97; TM7LN1

应用说明

应用建议
应用 推荐稀释比
FACS1:50
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
IP1:50
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 U937
实际分子量 ~ 75 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 976 Human ADGRE5

Swiss-port # P48960 Human CD97 antigen

基因名称 ADGRE5
全名 adhesion G protein-coupled receptor E5
背景介绍 This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
生物功能 Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity). [UniProt]
细胞定位 Cell membrane; Multi-pass membrane protein. CD97 antigen subunit alpha: Secreted, extracellular space. [UniProt]
预测分子量 92 kDa
翻译后修饰 Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG41632 anti-CD97 antibody WB image

    Western blot: U937 cell lysate stained with ARG41632 anti-CD97 antibody.