ARG65671
anti-CK1 epsilon antibody
anti-CK1 epsilon antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CK1 epsilon |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CK1 epsilon |
| 抗原物种 | Human |
| 抗原 | Fusion protein around the C-terminus of Human CK1 epsilon. |
| 偶联标记 | Un-conjugated |
| 別名 | tau; CK1epsilon; Casein kinase I isoform epsilon; AI426939; CKIe; CKI-epsilon; AW457082; AI551861; EC 2.7.11.1; KC1epsilon |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | IHC: Human cervical cancer. WB: Hela and A431 cell. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.05% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 3.1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CSNK1E |
| 全名 | casein kinase 1, epsilon |
| 背景介绍 | This locus represents naturally occurring readthrough transcription between the neighboring LOC400927 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene) and CSNK1E (casein kinase I isoform epsilon) genes on chromosome 22. The readthrough transcript encodes the same protein as the downstream gene product (casein kinase I isoform epsilon). [provided by RefSeq, Feb 2014] |
| 生物功能 | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 47 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG65671 anti-CK1 epsilon antibody WB image
Western blot: 40 µg of 1) HeLa and 2) A431 cell lysates stained with ARG65671 anti-CK1 epsilon antibody at 1:1550 dilution.
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ARG65671 anti-CK1 epsilon antibody IHC-P image
Immunohistochemistry: paraffin-embedded Human cervical cancer tissue stained with ARG65671 anti-CK1 epsilon antibody (left) at 1:60 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200)
