ARG57953
anti-COX7A2L antibody
anti-COX7A2L antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes COX7A2L |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | COX7A2L |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-114 of Human COX7A2L (NP_004709.2). |
| 偶联标记 | Un-conjugated |
| 別名 | SIG81; Cytochrome c oxidase subunit 7A-related protein, mitochondrial; COX7RP; COX7a-related protein; EB1; Cytochrome c oxidase subunit VIIa-related protein; COX7AR |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse brain | ||||
| 实际分子量 | 13 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O14548 Human Cytochrome c oxidase subunit 7A-related protein, mitochondrial Swiss-port # Q61387 Mouse Cytochrome c oxidase subunit 7A-related protein, mitochondrial |
|---|---|
| 基因名称 | COX7A2L |
| 全名 | cytochrome c oxidase subunit VIIa polypeptide 2 like |
| 背景介绍 | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity). Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity). [UniProt] |
| 细胞定位 | Mitochondrion inner membrane. [UniProt] |
| 预测分子量 | 13 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG57953 anti-COX7A2L antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG57953 anti-COX7A2L antibody at 1:1000 dilution.
