ARG44646
anti-CREB antibody
anti-CREB antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CREB |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | CREB |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | CREB1; CAMP Responsive Element Binding Protein 1; Cyclic AMP-Responsive Element-Binding Protein 1; CREB-1; Cyclic Adenosine 3',5'-Monophosphate Response Element-Binding Protein CREB; Cyclic Adenosine 3',5'-Monophosphate Response Element Binding Protein; CAMP-Responsive Element-Binding Protein 1; CAMP-Response Element-Binding Protein-1; Active Transcription Factor CREB; Transactivator Protein; CRE |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P16220 Human Cyclic AMP-responsive element-binding protein 1 Swiss-port # Q01147 Mouse Cyclic AMP-responsive element-binding protein 1 |
|---|---|
| 基因名称 | CREB1 |
| 全名 | CAMP Responsive Element Binding Protein 1 |
| 背景介绍 | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] |
| 生物功能 | Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG44646 anti-CREB antibody IHC-P image
Immunohistochemistry: Human Testis stained with ARG44646 anti-CREB antibody at 5 µg/mL dilution.
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ARG44646 anti-CREB antibody WB image
Western blot: U-2 OS stained with ARG44646 anti-CREB antibody at 1 µg/mL dilution.
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ARG44646 anti-CREB antibody IP image
Immunoprecipitation: U-2 OS lysate immunoprecipitated with 2.5 µg of ARG44646 anti-CREB antibody.
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ARG44646 anti-CREB antibody IHC-P image
Immunohistochemistry: Mouse Brain stained with ARG44646 anti-CREB antibody at 5 µg/mL dilution.
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ARG44646 anti-CREB antibody WB image
Western blot: NIH/3T3 and Mouse Brain stained with ARG44646 anti-CREB antibody at 1 µg/mL dilution.
