ARG56685
anti-CXCL11 / I-TAC antibody
anti-CXCL11 / I-TAC antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Neutralizing,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CXCL11 / I-TAC |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, IHC-P, Neut, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CXCL11 / I-TAC |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human I-TAC (CXCL11). (FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF) |
| 偶联标记 | Un-conjugated |
| 別名 | SCYB9B; SCYB11; C-X-C motif chemokine 11; Beta-R1; b-R1; Interferon gamma-inducible protein 9; I-TAC; Small-inducible cytokine B11; Interferon-inducible T-cell alpha chemoattractant; H174; IP-9; IP9 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CXCL11 |
| 全名 | chemokine (C-X-C motif) ligand 11 |
| 背景介绍 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] |
| 生物功能 | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [UniProt] |
| 产品亮点 | Related products: CXCL11 antibodies; CXCL11 ELISA Kits; Anti-Rabbit IgG secondary antibodies; Related news: circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity |
| 预测分子量 | 10 kDa |
检测图片 (5) Click the Picture to Zoom In
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ARG56685 anti-CXCL11 / I-TAC antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded sections of Human renal tumor with parenchyma tissue. The recommended ARG56685 anti-CXCL11 / I-TAC antibody concentration is 0.125 µg/mL- 0.25 µg/mL with an overnight incubation at 4°C. An HRP-labeled polymer detection system was used with a DAB chromogen.
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ARG56685 anti-CXCL11 / I-TAC antibody WB image
Western blot: 250 - 0.24 ng of Human I-TAC stained with ARG56685 anti-CXCL11 / I-TAC antibody, under reducing conditions.
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ARG56685 anti-CXCL11 / I-TAC antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded sections of Human renal tumor with parenchyma tissue. The recommended ARG56685 anti-CXCL11 / I-TAC antibody concentration is 0.125 µg/mL- 0.25 µg/mL with an overnight incubation at 4°C. An HRP-labeled polymer detection system was used with a DAB chromogen.
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ARG56685 anti-CXCL11 / I-TAC antibody WB image
Western blot: 250 - 0.24 ng of Human I-TAC stained with ARG56685 anti-CXCL11 / I-TAC antibody, under non-reducing conditions.
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ARG56685 anti-CXCL11 / I-TAC antibody standard curve image
Sandwich ELISA: ARG56685 anti-CXCL11 / I-TAC antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56794 anti-CXCL11 / I-TAC antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
