ARG56661

anti-CXCL2 / MIP2 antibody

anti-CXCL2 / MIP2 antibody for ELISA,Neutralizing,Western blot and Mouse,Rat

publication_link 参考文献1

概述

产品描述 Rabbit Polyclonal antibody recognizes CXCL2 / MIP2
反应物种 Ms, Rat
应用 ELISA, Neut, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CXCL2 / MIP2
抗原物种 Mouse
抗原 E.coli derived Recombinant Mouse MIP-2 (CXCL2).
(AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN)
偶联标记 Un-conjugated
別名 Gro-beta; SCYB2; HSF; CINC-2a; GROb; MGSA-b; SB-251353; MIP2A; MIP2; Hematopoietic synergistic factor; 5-73; C-X-C motif chemokine 2; MIP-2a; GRO2; Macrophage inflammatory protein 2-alpha; GRO-beta-T; Growth-regulated protein beta; MIP2-alpha

应用说明

应用建议
应用 推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG56771 as a detection antibody
Neut0.52 - 0.90 µg/ml (To yield [ND50] of the biological activity of mMIP - 2 (15.00 ng/ml) )
WB0.1 - 0.2 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.2)
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 114105 Rat CXCL2

GeneID: 20310 Mouse CXCL2

Swiss-port # P10889 Mouse C-X-C motif chemokine 2

Swiss-port # P30348 Rat C-X-C motif chemokine 2

基因名称 Cxcl2
全名 chemokine (C-X-C motif) ligand 2
背景介绍 This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
生物功能 Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. [UniProt]
预测分子量 11 kDa
翻译后修饰 The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.

检测图片 (3) Click the Picture to Zoom In

  • ARG56661 anti-CXCL2 / MIP2 antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-2 stained with ARG56661 anti-CXCL2 / MIP2 antibody, under reducing conditions.

  • ARG56661 anti-CXCL2 / MIP2 antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-2 stained with ARG56661 anti-CXCL2 / MIP2 antibody, under non-reducing conditions.

  • ARG56661 anti-CXCL2 / MIP2 antibody standard curve image

    Sandwich ELISA: ARG56661 anti-CXCL2 / MIP2 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56771 anti-CXCL2 / MIP-2 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.

文献引用

Self-recruited neutrophils trigger over-activated innate immune response and phenotypic change of cardiomyocytes in fulminant viral myocarditis

Neut / Mouse

Huihui Li et al.
Cell discovery,  (2023)

publication_link

 

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