ARG56670
anti-CXCL7 / NAP2 antibody
anti-CXCL7 / NAP2 antibody for ELISA,Western blot and Human
概述
| 产品描述 | Goat Polyclonal antibody recognizes CXCL7 / NAP2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CXCL7 / NAP2 |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human NAP-2 (CXCL7). (AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD) |
| 偶联标记 | Un-conjugated |
| 別名 | CTAP3; Platelet basic protein; SCYB7; Macrophage-derived growth factor; THBGB; CTAPIII; C-X-C motif chemokine 7; Beta-TG; NAP-2; Small-inducible cytokine B7; TGB; THBGB1; CTAP-III; PBP; MDGF; TC2; Low-affinity platelet factor IV; Leukocyte-derived growth factor; TC1; 74; 73; 1-66; B-TG1; 1-63; CXCL7; TGB1; 1-81; LDGF; LA-PF4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PPBP |
| 全名 | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| 背景介绍 | The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014] |
| 生物功能 | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. [UniProt] |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)). Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor. NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils. NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets. |
检测图片 (3) Click the Picture to Zoom In
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ARG56670 anti-CXCL7 / NAP2 antibody WB image
Western blot: 250 - 0.24 ng of Human NAP-2 stained with ARG56670 anti-CXCL7 / NAP2 antibody, under reducing conditions.
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ARG56670 anti-CXCL7 / NAP2 antibody WB image
Western blot: 250 - 0.24 ng of Human NAP-2 stained with ARG56670 anti-CXCL7 / NAP2 antibody, under non-reducing conditions.
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ARG56670 anti-CXCL7 / NAP2 antibody standard curve image
Sandwich ELISA: ARG56670 anti-CXCL7 / NAP2 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56780 anti-CXCL7 / NAP-2 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
