ARG67142
anti-CXCR4 antibody
anti-CXCR4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CXCR4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CXCR4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to Human CXCR4. |
| 偶联标记 | Un-conjugated |
| 別名 | CXCR4; C-X-C Motif Chemokine Receptor 4; LESTR; Fusin; HM89; D2S201E; NPYY3R; HSY3RR; NPY3R; CD184; NPYR; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lipopolysaccharide-Associated Protein 3; Stromal Cell-Derived Factor 1 Receptor; Chemokine (C-X-C Motif) Receptor 4; C-X-C Chemokine Receptor Type 4; LPS-Associated Protein 3; SDF-1 Receptor; CD184 Antigen; LAP-3; NPYRL; FB22; LCR1 ; Seven-Transmembrane-Segment Receptor, Spleen; Chemokine (C-X-C Motif), Receptor 4 (Fusin); Seven Transmembrane Helix Receptor; Neuropeptide Y Receptor Y3; Neuropeptide Y3 Receptor; WHIMS1; CXC-R4; CXCR-4; WHIMS; LAP3; WHIM |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 47-64 kda |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS, 0.02% Sodium azide, 0.5% BSA and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA, 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CXCR4 |
| 全名 | C-X-C Motif Chemokine Receptor 4 |
| 背景介绍 | This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. [UniProt] |
| 细胞定位 | Cell junction, Cell membrane, Endosome, Lysosome, Membrane. [UniProt] |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Isopeptide bond, Phosphoprotein, Proteoglycan, Sulfation, Ubl conjugation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG67142 anti-CXCR4 antibody IHC-P image
Immunohistochemistry: Human Breast Carcinoma stained with ARG67142 anti-CXCR4 antibody at 1:200 dilution.
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ARG67142 anti-CXCR4 antibody WB image
Western blot: Rat Brai, HeLa and HEK293 stained with ARG67142 anti-CXCR4 antibody at 1:1000 dilution.
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ARG67142 anti-CXCR4 antibody IHC-P image
Immunohistochemistry: Human Tonsil Tissue stained with ARG67142 anti-CXCR4 antibody at 1:200 dilution.
