ARG44607
anti-CXCR7 / CD187 antibody [10D1-J16] (APC)
anti-CXCR7 / CD187 antibody [10D1-J16] (APC) for Flow cytometry and Human
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody recognizes CXCR7 / CD187 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 10D1-J16 |
| 同位型 | IgG2a kappa |
| 靶点名称 | CXCR7 / CD187 |
| 抗原物种 | Human |
| 偶联标记 | APC |
| 別名 | ACKR3; Atypical Chemokine Receptor 3; GPR159; RDC1; Chemokine Orphan Receptor 1; CMKOR1; CXCR7; G-Protein Coupled Receptor RDC1 Homolog; Chemokine (C-X-C Motif) Receptor 7; C-X-C Chemokine Receptor Type 7 ; G-Protein Coupled Receptor 159; CXC-R7; CXCR-7; RDC-1; G Protein-Coupled Receptor |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACKR3 |
| 全名 | Atypical Chemokine Receptor 3 |
| 背景介绍 | This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008] |
| 生物功能 | Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. [Uniprot] |
| 细胞定位 | Cell membrane, Endosome, Membrane. [Uniprot] |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
-
ARG44607 anti-CXCR7 / CD187 antibody [10D1-J16] (APC) FACS image
Flow Cytometry: MCF-7 stained with ARG44607 anti-CXCR7 / CD187 antibody [10D1-J16] (APC) at 10 μl/ 100 μl dilution.
