ARG67126

anti-CXCR7 / CD187 antibody

anti-CXCR7 / CD187 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes CXCR7 / CD187
反应物种 Hu
预测物种 Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CXCR7 / CD187
抗原物种 Human
偶联标记 Un-conjugated
別名 ACKR3; Atypical Chemokine Receptor 3; GPR159; RDC1; Chemokine Orphan Receptor 1; CMKOR1; CXCR7; G-Protein Coupled Receptor RDC1 Homolog; Chemokine (C-X-C Motif) Receptor 7; C-X-C Chemokine Receptor Type 7 ; G-Protein Coupled Receptor 159; CXC-R7; CXCR-7; RDC-1; G Protein-Coupled Receptor

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:100
WB1:500 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purification with Protein A.
缓冲液 PBS and 0.09% (W/V) Sodium azide.
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 57007 Human ACKR3

Swiss-port # P25106 Human Atypical chemokine receptor 3

基因名称 ACKR3
全名 Atypical Chemokine Receptor 3
背景介绍 This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]
生物功能 Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. [Uniprot]
细胞定位 Cell membrane, Endosome, Membrane. [Uniprot]
预测分子量 41 kDa
翻译后修饰 Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation. [Uniprot]

检测图片 (2) Click the Picture to Zoom In

  • ARG67126 anti-CXCR7 / CD187 antibody WB image

    Western blot: U-251 stained with ARG67126 anti-CXCR7 / CD187 antibody at 1:1000 dilution.

  • ARG67126 anti-CXCR7 / CD187 antibody IHC-P image

    Immunohistochemistry: Human testis stained with ARG67126 anti-CXCR7 / CD187 antibody.