ARG66771
anti-Calcitonin antibody [SQab20204]
anti-Calcitonin antibody [SQab20204] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab20204] recognizes Calcitonin |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab20204 |
| 同位型 | IgG |
| 靶点名称 | Calcitonin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to residues in Human Calcitonin. |
| 偶联标记 | Un-conjugated |
| 別名 | CALC1; Calcitonin carboxyl-terminal peptide; CCP; PDN-21; CT |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Medullary thyroid carcinoma. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CALCA |
| 全名 | Calcitonin |
| 背景介绍 | This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2014] |
| 生物功能 | Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Katacalcin is a potent plasma calcium-lowering peptide. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 14 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66771 anti-Calcitonin antibody [SQab20204] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human medullary thyroid carcinoma tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66771 anti-Calcitonin antibody [SQab20204] at 18°C - 25°C for 30 minutes.
