ARG10475
anti-Cardiac Troponin C antibody [7B9]
anti-Cardiac Troponin C antibody [7B9] for ELISA,Immunoassay,Purification,Western blot and Human
Cell Biology and Cellular Response antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [7B9] recognizes Cardiac Troponin C |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, IA, Puri, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 7B9 |
| 同位型 | IgG1 |
| 靶点名称 | Cardiac Troponin C |
| 抗原物种 | Human |
| 抗原 | human cardiac troponin complex |
| 偶联标记 | Un-conjugated |
| 別名 | CMH13; Troponin C, slow skeletal and cardiac muscles; CMD1Z; TNC; TNNC; TN-C |
应用说明
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A affinity purified. |
| 缓冲液 | PBS (pH 7.4) and 0.1% Sodium azide |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 1.0-2.0 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P63316 Human Troponin C, slow skeletal and cardiac muscles |
|---|---|
| 基因名称 | TNNC1 |
| 全名 | troponin C type 1 (slow) |
| 背景介绍 | Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008] |
| 生物功能 | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Signaling Transduction antibody |
| 预测分子量 | 18 kDa |
