ARG55067
anti-Catalase antibody [626CT4.3.8]
anti-Catalase antibody [626CT4.3.8] for Western blot and Human,Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody; Peroxisome Marker antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Catalase |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Bov, Rat, Pig, Zfsh |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 626CT4.3.8 |
| 同位型 | IgG2a |
| 靶点名称 | Catalase |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 152-180 (Center) of Human Catalase. |
| 偶联标记 | Un-conjugated |
| 別名 | Catalase; EC 1.11.1.6 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | K562 |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | Crude Ascites and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CAT |
| 全名 | catalase |
| 背景介绍 | This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009] |
| 生物功能 | Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. [UniProt] |
| 细胞定位 | Peroxisome. |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody; Peroxisome Marker antibody |
| 预测分子量 | 60 kDa |
| 翻译后修饰 | The N-terminus is blocked. |
检测图片 (1) Click the Picture to Zoom In
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ARG55067 anti-Catalase antibody WB image
Western blot: 35 µg of K562 cell lysate stained with ARG55067 anti-Catalase antibody.
