ARG67081
anti-Claudin 6 antibody [SQab30353]
anti-Claudin 6 antibody [SQab30353] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab30353] recognizes Claudin 6 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30353 |
| 同位型 | IgG |
| 靶点名称 | Claudin 6 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Claudin 6. |
| 偶联标记 | Un-conjugated |
| 別名 | CLDN6; Claudin 6; Claudin-6; Skullin |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CLDN6 |
| 全名 | Claudin 6 |
| 背景介绍 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
| 生物功能 | Plays a major role in tight junction-specific obliteration of the intercellular space. |
| 细胞定位 | Cell junction, Cell membrane, Membrane, Tight junction |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG67081 anti-Claudin 6 antibody [SQab30353] HC-P image
Immunohistochemistry: Human ovarian cancer stained with ARG67081 anti-Claudin 6 antibody [SQab30353].
