ARG59478

anti-Collagen X antibody

anti-Collagen X antibody for ICC/IF,Western blot and Human,Mouse,Pig,Rat

publication_link 参考文献3

概述

产品描述 Rabbit Polyclonal antibody recognizes Collagen X
反应物种 Hu, Ms, Rat, Pig
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Collagen X
抗原物种 Human
抗原 Synthetic peptide of Human Collagen X.
偶联标记 Un-conjugated
別名 Collagen alpha-1(X) chain

应用说明

应用建议
应用 推荐稀释比
ICC/IFAssay-dependent
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 12813 Mouse COL10A1

GeneID: 1300 Human COL10A1

Swiss-port # Q03692 Human Collagen alpha-1(X) chain

Swiss-port # Q05306 Mouse Collagen alpha-1(X) chain

基因名称 COL10A1
全名 collagen, type X, alpha 1
背景介绍 This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]
生物功能 Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage. [UniProt]
细胞定位 Secreted, extracellular space, extracellular matrix. [UniProt]
预测分子量 66 kDa
翻译后修饰 Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG59478 anti-Collagen X antibody ICC/IF image

    Immunofluorescence: human articular chondrocytes stained with ARG20787 anti-Collagen II antibody, pre-adsorbed and ARG59478 anti-Collagen X antibody.

    From Yuxuan Zhang et al. Comput Math Methods Med (2022), doi: 10.1155/2022/8388473, Fig. 3 (e) (f) (g).

文献引用

Nanohydroxyapatite Hydrogel Can Promote the Proliferation and Migration of Chondrocytes and Better Repair Talar Articular Cartilage

ICC/IF / Mouse

Yuxuan Zhang et al.
Computational and Mathematical Methods in Medicine ,  (2022)

publication_link

 

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Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway

WB / Pig

Zi-Miao Liu et al.
Bone Joint Res.,  (2021)

publication_link

 

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Shockwave Treatment Enhances the Extracellular Matrix Production in Articular Chondrocyte Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway.

WB / Pig

Shen Po-Chih et al.
Preprint.,  (2020)

publication_link

 

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