ARG55218
anti-Complexin 1 antibody
anti-Complexin 1 antibody for Western blot and Mouse
Cell Biology>Cell Cycle>Cell Cycle Inhibitors>Cip / Kip> antibody; Signal Transduction>Cytoskeleton / ECM>Cytoskeleton>Microfilaments>Actin etc>Actin Assembly> antibody; Signal Transduction>Signaling Pathway>G Protein Signaling>Heterotrimeric G Proteins>G Proteins> antibody; Epigenetics and Nuclear Signaling>Cell cycle>Cell Cycle Inhibitors>Cip/Kip> antibody; Cancer>Cell cycle>Cell cycle inhibitors>Cip/kip> antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Complexin 1 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Bov, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Complexin 1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 51-83 (Center) of Human Complexin 1. |
| 偶联标记 | Un-conjugated |
| 別名 | 921-L; Complexin-2; Synaphin-1; CPX II; CPX-2; CPX2; Complexin II; Hfb1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse brain |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CPLX2 |
| 全名 | complexin 2 |
| 背景介绍 | Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm, cytosol. Note=Enriched at synaptic-releasing sites in mature neurons. |
| 研究领域 | Cell Biology>Cell Cycle>Cell Cycle Inhibitors>Cip / Kip> antibody; Signal Transduction>Cytoskeleton / ECM>Cytoskeleton>Microfilaments>Actin etc>Actin Assembly> antibody; Signal Transduction>Signaling Pathway>G Protein Signaling>Heterotrimeric G Proteins>G Proteins> antibody; Epigenetics and Nuclear Signaling>Cell cycle>Cell Cycle Inhibitors>Cip/Kip> antibody; Cancer>Cell cycle>Cell cycle inhibitors>Cip/kip> antibody |
| 预测分子量 | 15 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55218 anti-Complexin 1 antibody WB image
Western blot: 35 µg of Mouse brain lysate stained with ARG55218 anti-Complexin 1 antibody at 1:1000 dilution.
