ARG23977
anti-Cytokeratin 7 antibody [LP5K] (FITC)
anti-Cytokeratin 7 antibody [LP5K] (FITC) for Flow cytometry,ICC/IF and Human
CK7/CK20 Carcinoma Study antibody
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [LP5K] recognizes Cytokeratin 7 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | LP5K |
| 同位型 | IgG2b |
| 靶点名称 | Cytokeratin 7 |
| 抗原物种 | Human |
| 抗原 | Cytoskeletal proteins from cultured HeLa cells. |
| 偶联标记 | FITC |
| 別名 | SCL; Sarcolectin; CK-7; Cytokeratin-7; CK7; Keratin, type II cytoskeletal 7; Keratin-7; K7; K2C7; Type-II keratin Kb7 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Ammonium sulphate precipitation followed by ion exchange chromatography. |
| 缓冲液 | PBS, 0.1% Sodium azide and 0.1% BSA. |
| 抗菌剂 | 0.1% Sodium azide |
| 稳定剂 | 0.1% BSA |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KRT7 |
| 全名 | keratin 7, type II |
| 背景介绍 | Cytokeratin 7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 研究领域 | CK7/CK20 Carcinoma Study antibody |
| 预测分子量 | 51 kDa |
| 翻译后修饰 | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. [UniProt] |
