ARG20785

anti-Cytokeratin 7 antibody [RCK105]

anti-Cytokeratin 7 antibody [RCK105] for Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

CK7/CK20 Carcinoma Study antibody

概述

产品描述 Mouse Monoclonal antibody [RCK105] recognizes Cytokeratin 7
反应物种 Hu, Ms, Rat
预测物种 Cat, Dog, Hm, Pig
应用 FACS, ICC/IF, IHC-Fr, IHC-P, WB
宿主 Mouse
克隆 Monoclonal
克隆号 RCK105
同位型 IgG1
靶点名称 Cytokeratin 7
抗原物种 Human
抗原 A cytokeratin from Human bladder carcinoma cell line T24 and SP2/0-Ag14 Mouse myeloma cells.
偶联标记 Un-conjugated
別名 SCL; Sarcolectin; CK-7; Cytokeratin-7; CK7; Keratin, type II cytoskeletal 7; Keratin-7; K7; K2C7; Type-II keratin Kb7

应用说明

应用建议
应用 推荐稀释比
FACS1:100 - 1:200
ICC/IF1:100 - 1:200
IHC-Fr1:100 - 1:200
IHC-PAssay-dependent
WB1:100 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purification with Protein A/G.
缓冲液 PBS and 0.08% Sodium azide
抗菌剂 0.08% Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 110310 Mouse KRT7

GeneID: 300242 Rat KRT7

GeneID: 3855 Human KRT7

基因名称 KRT7
全名 keratin 7, type II
背景介绍 Cytokeratin 7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
生物功能 Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). [UniProt]
研究领域 CK7/CK20 Carcinoma Study antibody
预测分子量 51 kDa
翻译后修饰 Arg-20 is dimethylated, probably to asymmetric dimethylarginine.