ARG43835

anti-DLST antibody

anti-DLST antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes DLST.
反应物种 Hu
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Dihydrolipoamide S-Succinyltransferase
抗原 Recombinant fragment of human DLST (aa.188 - 453).
偶联标记 Un-conjugated
別名 DLST; Dihydrolipoamide S-Succinyltransferase; OGDC-E2; KGD2; DLTS; Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex, Mitochondrial; Dihydrolipoamide S-Succinyltransferase (E2 Component Of 2-Oxo-Glutarate Complex); 2-Oxoglutarate Dehydrogenase Complex Component E2; EC 2.3.1.61; E2K; Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex; Dihydrolipoyllysine-Residue Succinyltransferase; EC 2.3.1; PGL7

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:100-1:1000
IHC-P1:100-1:1000
WB1:500-1:3000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purified
缓冲液 Tris-Glycine (pH 7) with 0.01% Thimerosal
抗菌剂 0.01% Thimerosal
浓度 700 µg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 1743 Human DLST

Swiss-port # P36957 Human Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarat

基因名称 DLST
全名 Dihydrolipoamide S-Succinyltransferase
背景介绍 This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
生物功能 A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
细胞定位 Mitochondrion, Nucleus
翻译后修饰 Acetylation, Phosphoprotein

检测图片 (3) Click the Picture to Zoom In

  • ARG43835 anti-DLST antibody IHC-P image

    Immunohistochemistry: Human carcinoma stained with ARG43835 anti-DLST antibody at 1:500 dilution.

  • ARG43835 anti-DLST antibody WB image

    Western blot: A431 stained with ARG43835 anti-DLST antibody at 1:1000 dilution.

  • ARG43835 anti-DLST antibody ICC/IF image

    Immunofluorescence: A431 cells stained with ARG43835 anti-DLST antibody at 1:500 dilution.