ARG54395
anti-DR3 / TNFRSF25 antibody
anti-DR3 / TNFRSF25 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DR3 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody recognizes full-length human and mouse DR3 (59kDa). |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DR3 / TNFRSF25 |
| 抗原物种 | Human |
| 抗原 | Peptide corresponding to aa 25-40 at the N-terminus of human DR3 (accession no. AAQ88676). |
| 偶联标记 | Un-conjugated |
| 別名 | WSL-1; Apo-3; Apoptosis-mediating receptor TRAMP; DDR3; DR3; Protein WSL; Protein WSL-1; TRAMP; Apoptosis-inducing receptor AIR; TNFRSF12; Death receptor 3; LARD; Apoptosis-mediating receptor DR3; TR3; APO-3; Lymphocyte-associated receptor of death; Tumor necrosis factor receptor superfamily member 25; WSL-LR |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Jurkat |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunoaffinity chroma-tography |
| 缓冲液 | PBS (pH 7.4) and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q93038 Human Tumor necrosis factor receptor superfamily member 25 |
|---|---|
| 基因名称 | TNFRSF25 |
| 全名 | tumor necrosis factor receptor superfamily, member 25 |
| 背景介绍 | Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain-containing receptors, TNFR1 and Fas. Another cell death receptor was recently identified and designated DR3, Wsl-1, Apo-3, TRAMP, and LARD. DR3 is widely expressed in tissues enriched in lymphocytes including peripheral blood, thymus, and spleen. Like TNFR1, DR3 induces apoptosis and NF- B activation. |
| 生物功能 | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Glycosylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG54395 anti-DR3 / TNFRSF25 antibody WB image
Western Blot: Jurkat stained with ARG54395 anti-DR3 antibody at 1 μg/ml dilution.
