ARG65023
anti-DSG1 / Desmoglein 1 antibody
anti-DSG1 / Desmoglein 1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes DSG1 / Desmoglein 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DSG1 / Desmoglein 1 |
| 抗原物种 | Human |
| 抗原 | C-YTTSDTLKPSVHVHD |
| 偶联标记 | Un-conjugated |
| 別名 | PPKS1; Desmoglein-1; SPPK1; DGI; EPKHIA; CDHF4; DG1; Desmosomal glycoprotein 1; DSG; Cadherin family member 4; Pemphigus foliaceus antigen; EPKHE |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq, Jul 2008] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 114 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG65023 anti-DSG1 / Desmoglein 1 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Skin. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65023 anti-DSG1 / Desmoglein 1 antibody at 3.8 µg/ml dilution followed by AP-staining.
