ARG44816

anti-DTX3L antibody

anti-DTX3L antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

概述

产品描述 Mouse Monoclonal antibody recognizes DTX3L
反应物种 Hu
应用 IHC-P
宿主 Mouse
克隆 Monoclonal
同位型 IgG1
靶点名称 DTX3L
抗原物种 Human
抗原表位 RVRRKLESYF QSSKSSGGGE CTVSTQEHEA PGTFRVEFSE RAAKERVLKK GEHQILVDEK PVPIFLVPTE NSIKKNTRPQ ISSLTQSQAE TPSGDMHQHE
偶联标记 Un-conjugated
別名 DTX3L; Deltex E3 Ubiquitin Ligase 3L; BBAP; RNF143; RING-Type E3 Ubiquitin Transferase DTX3L; B-Lymphoma- And BAL-Associated Protein; E3 Ubiquitin-Protein Ligase DTX3L; Rhysin-2; Rhysin2; Deltex 3 Like, E3 Ubiquitin Ligase; Deltex 3-Like (Drosophila); Protein Deltex-3-Like; Deltex 3-Like; EC 2.3.2.27; Rhysin 2

应用说明

应用建议
应用 推荐稀释比
IHC-P1:200
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Protein A purification
缓冲液 PBS with 0.09% sodium azide
抗菌剂 0.09% sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 151636 Human DTX3L

Swiss-port # Q8TDB6 Human E3 ubiquitin-protein ligase DTX3L

基因名称 DTX3L
全名 Deltex E3 Ubiquitin Ligase 3L
背景介绍 Enables several functions, including STAT family protein binding activity; ubiquitin-like protein ligase binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of protein localization; and protein ubiquitination. Located in cytosol; lysosome; and nucleoplasm. Part of protein-containing complex. Colocalizes with early endosome and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
生物功能 In association with PARP9, plays a role in antiviral responses by mediating 'Lys-48'-linked ubiquitination of encephalomyocarditis virus (EMCV) and human rhinovirus (HRV) C3 proteases and thus promoting their proteasomal-mediated degradation. [Uniprot]
细胞定位 Cytoplasm, Endosome, Lysosome, Membrane, Nucleus. [Uniprot]
翻译后修饰 Acetylation, Phosphoprotein, Ubl conjugation. [Uniprot]

检测图片 (1) Click the Picture to Zoom In

  • ARG44816 anti-DTX3L antibody IHC-P image

    Immunohistochemistry: Human tonsil stained with ARG44816 anti-DTX3L antibody at 5 µg/mL dilution.