ARG58558
anti-Desmoglein 3 antibody [5G11]
anti-Desmoglein 3 antibody [5G11] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [5G11] recognizes Desmoglein 3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5G11 |
| 同位型 | IgG1, kappa |
| 靶点名称 | Desmoglein 3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to the extracellular portion of Human Desmoglein 3. |
| 偶联标记 | Un-conjugated |
| 別名 | PVA; 130 kDa pemphigus vulgaris antigen; CDHF6; Cadherin family member 6; Desmoglein-3 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DSG3 |
| 全名 | desmoglein 3 |
| 背景介绍 | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008] |
| 生物功能 | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt] |
| 细胞定位 | Cell surface. [UniProt] |
| 预测分子量 | 108 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58558 anti-Desmoglein 3 antibody [5G11] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human skin stained with ARG58558 anti-Desmoglein 3 antibody [5G11]. Antigen Retrieval: Boil tissue section in 10mM Citrate buffer (pH 6.0) for 10-20 min.
