ARG45065
anti-EB1 / EB2 / EB3 antibody [KT65]
anti-EB1 / EB2 / EB3 antibody [KT65] for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rat Monoclonal antibody [KT65] recognizes EB1 / EB2 / EB3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | KT65 |
| 同位型 | IgG2a |
| 靶点名称 | EB1 / EB2 / EB3 |
| 抗原物种 | Mouse |
| 抗原 | [KT65] was generated from a GST fusion protein containing amino acids from the C-terminal region mouse EB1. This sequence is highly conserved in human and rat EB1. |
| 偶联标记 | Un-conjugated |
| 別名 | MAPRE1; Microtubule Associated Protein RP/EB Family Member 1; EB1; Microtubule-Associated Protein RP/EB Family Member 1; Adenomatous Polyposis Coli-Binding Protein EB1; APC-Binding Protein EB1; End-Binding Protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G Purified. |
| 缓冲液 | PBS, 0.05% NaN3 |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MAPRE1/2/3 |
| 全名 | Microtubule Associated Protein RP/EB Family Member 1 |
| 背景介绍 | The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008] |
| 生物功能 | Functions downstream of Rho GTPases and DIAPH1 in stable microtubule formation. May play a role in cell migration. [Uniprot] |
| 细胞定位 | Cytoplasm, Cytoskeleton, Golgi apparatus, Microtubule. [Uniprot] |
| 预测分子量 | 30 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein. [Uniprot] |
