ARG55949
anti-ECM1 / Secretory Component antibody [SC05]
anti-ECM1 / Secretory Component antibody [SC05] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [SC05] recognizes ECM1 / Secretory Component |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | FACS, ICC/IF, IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SC05 |
| 同位型 | IgG1, kappa |
| 靶点名称 | ECM1 / Secretory Component |
| 抗原物种 | Human |
| 抗原 | Secretory component protein isolated from Human colostrum. |
| 偶联标记 | Un-conjugated |
| 別名 | URBWD; Extracellular matrix protein 1; Secretory component p85 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ECM1 |
| 全名 | extracellular matrix protein 1 |
| 背景介绍 | This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
| 生物功能 | Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. [UniProt] |
| 细胞定位 | Cell surface and cytoplasmic |
| 预测分子量 | 61 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55949 anti-ECM1 / Secretory Component antibody [SC05] IHC-P image
Immunohistochemistry: Human colon carcinoma stained with ARG55949 anti-ECM1 / Secretory Component antibody [SC05].
