ARG44826
anti-EXOSC10 / Rrp6p antibody
anti-EXOSC10 / Rrp6p antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes EXOSC10 / Rrp6p |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | EXOSC10 / Rrp6p |
| 抗原物种 | Human |
| 抗原表位 | PFRMFLPSLG HRAPVSQAAK FDPSTKIYEI SNRWKLAQVQ VQKDSKEAVK KKAAEQTAAR EQAKEACKAA AEQAISVRQQ VVLENAAKKR ERATSDPRTT EQKQEKKRLK ISKKPKDPEP PEKEFTPYDY SQSDFKAFAG NSKSKVSSQF DPNKQTPSGK |
| 偶联标记 | Un-conjugated |
| 別名 | EXOSC10; Exosome Component 10; PM/Scl-100; RRP6; PM-Scl; PMSCL2; Rrp6p; P2; P3; P4; P100 Polymyositis-Scleroderma Overlap Syndrome-Associated Autoantigen; Polymyositis/Scleroderma Autoantigen 100 KDa; Polymyositis/Scleroderma Autoantigen 2; Exosome Complex Component 10; PMSCL; Polymyositis/Scleroderma Autoantigen 2 (100kD); Polymyositis/Scleroderma Autoantigen 2, 100kDa; Autoantigen PM/Scl 2; Autoantigen PM-SCL; EC 3.1.13.- |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EXOSC10 |
| 全名 | Exosome Component 10 |
| 背景介绍 | Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Regulates metabolism of C9orf72-derived repeat RNA that can be translated into toxic dipeptide repeat proteins. [UniProt] |
| 细胞定位 | Cytoplasm, Exosome, Nucleus. [UniProt] |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG44826 anti-EXOSC10/Rrp6p antibody IHC-P image
Immunohistochemistry: Human skin stained with ARG44826 anti-EXOSC10/Rrp6p antibody at 5 µg/mL dilution.
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ARG44826 anti-EXOSC10/Rrp6p antibody WB image
Western blot: HEK293 stained with ARG44826 anti-EXOSC10/Rrp6p antibody at 1 µg/mL dilution.
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ARG44826 anti-EXOSC10/Rrp6p antibody IP image
Immunoprecipitation: HEK293 lysate immunoprecipitated with 2.5 µg of ARG44826 anti-EXOSC10/Rrp6p antibody.
