概述

产品描述	Rabbit Polyclonal antibody recognizes Eotaxin
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	Eotaxin
抗原物种	Human
抗原	Recombinant fusion protein corresponding to aa. 1-97 of Human Eotaxin (NP_002977.1).
偶联标记	Un-conjugated
別名	SCYA11; C-C motif chemokine 11; Eosinophil chemotactic protein; Eotaxin; Small-inducible cytokine A11

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:100 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	20 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 20292 Mouse CCL11 GeneID: 29397 Rat CCL11 GeneID: 6356 Human CCL11 Swiss-port # P48298 Mouse Eotaxin Swiss-port # P51671 Human Eotaxin Swiss-port # P97545 Rat Eotaxin More
基因名称	CCL11
全名	chemokine (C-C motif) ligand 11
背景介绍	This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
生物功能	In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. [UniProt]
细胞定位	Secreted. [UniProt]
预测分子量	11 kDa
翻译后修饰	O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues. [UniProt]

检测图片 (1) Click the Picture to Zoom In