ARG52274
anti-EphrinB phospho (Tyr317) antibody
anti-EphrinB phospho (Tyr317) antibody for Western blot and Rat
Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EphrinB phospho (Tyr317) |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms, Bov, Chk, Xenopus laevis, Zfsh |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EphrinB |
| 抗原物种 | Chicken |
| 抗原 | Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr317 conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | EPH-like kinase 5; Developmentally-regulated Eph-related tyrosine kinase; Hek5; Renal carcinoma antigen NY-REN-47; EPH tyrosine kinase 3; Tyrosine-protein kinase receptor EPH-3; DRT; ELK-related tyrosine kinase; Tyrosine-protein kinase TYRO5; Ephrin type-B receptor 2; hEK5; PCBC; EPHT3; Tyro5; EK5; EC 2.7.10.1; CAPB; ERK |
应用说明
| 应用建议 |
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| 应用说明 | Specific for the ~46k EphrinB protein phosphorylated at Tyr317. The immunolabeling of the EphrinB band is blocked by treatment with λ-phosphatase. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | EPHB2 |
|---|---|
| 全名 | EPH receptor B2 |
| 背景介绍 | EphrinB proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vanderhaeghen, 1998; Dufour et al., 2003; Oike et al., 2002). EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work suggests that phosphorylation of a specific EphrinB residue (Tyr298) plays a key role in EphrinB signaling (Kalo, et al., 2001). |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody |
| 预测分子量 | 117 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG52274 anti-EphrinB phospho (Tyr317) antibody WB image
Western blot: Rat testes lysate showing phospho-specific immunolabeling of the ~46k Ephrin B protein phosphorylated at Tyr 317 stained with ARG52274 anti-EphrinB phospho (Tyr317) antibody.
