ARG65320
anti-FANCL antibody
anti-FANCL antibody for Western blot and Human
Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes FANCL |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize both isoforms (NP_001108108.1; NP_060532.2). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FANCL |
| 抗原物种 | Human |
| 抗原 | C-QNLKDVLEIDFP |
| 偶联标记 | Un-conjugated |
| 別名 | FAAP43; EC 6.3.2.-; E3 ubiquitin-protein ligase FANCL; Fanconi anemia group L protein; Fanconi anemia-associated polypeptide of 43 kDa; PHF9; POG |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 43 kDa |
| 翻译后修饰 | The RING-type zinc finger domain is monoubiquitinated in the presence of UBE2T and UBE2W. |
检测图片 (1) Click the Picture to Zoom In
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ARG65320 anti-FANCL antibody WB image
Western Blot: Human Bone Marrow lysate (35 µg protein in RIPA buffer) stained with ARG65320 anti-FANCL antibody at 1 µg/ml dilution.
