ARG67058
anti-FCGRT antibody [SQab30340]
anti-FCGRT antibody [SQab30340] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab30340] recognizes FCGRT |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30340 |
| 同位型 | IgG |
| 靶点名称 | FCGRT |
| 抗原物种 | Human |
| 抗原 | Recombinant protein fragment of FCGRT |
| 偶联标记 | Un-conjugated |
| Protein Full name | IgG receptor FcRn large subunit p51 |
| 別名 | FCGRT; Fc Gamma Receptor And Transporter ; Neonatal Fc Receptor; FcgammaRn; FcRn; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor; Transmembrane Alpha Chain Of The Neonatal Receptor; Fc Fragment Of IgG, Receptor, Transporter, Alpha; IgG Fc Fragment Receptor Transporter Alpha Chain; Fc Fragment Of IgG Receptor And Transporter; IgG Receptor FcRn Large Subunit P51; FCRN; Major Histocompatibility Complex Class I-Like Fc Receptor; Immunoglobulin Receptor, Intestinal, Heavy Chain; Neonatal Fc-Receptor For Ig; FCRN Alpha-Chain; FcRn Alpha Chai; Alpha-Chain |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P55899 Human IgG receptor FcRn large subunit p51 |
|---|---|
| 基因名称 | FCGRT |
| 全名 | Fc Gamma Receptor And Transporter |
| 背景介绍 | This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
| 生物功能 | IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation. |
| 细胞定位 | Cell membrane, Endosome, Membrane. [UniProt] |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67058 anti-FCGRT antibody [SQab30340] IHC-P image
Immunohistochemistry: Human tonsil tissue stained with ARG67058 anti-FCGRT antibody [SQab30340] at 1:100 dilution.
