ARG43767

anti-FNDC5 antibody

anti-FNDC5 antibody for Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes FNDC5
反应物种 Hu, Ms, Rat
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 FNDC5
抗原物种 Human
抗原 Synthetic peptide corresponding to Human FNDC5.
偶联标记 Un-conjugated
別名 irisin; FRCP2; Fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 20-25 kDa

属性

形式 Liquid
纯化 Affinity Purified
缓冲液 50 mM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.05% BSA, 40% Glycerol and 0.01% Sodium azide.
抗菌剂 0.01% Sodium azide
稳定剂 0.05% BSA and 40% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 252995 Human FNDC5

GeneID: 260327 Rat FNDC5

GeneID: 384061 Mouse FNDC5

基因名称 FNDC5
全名 fibronectin type III domain containing 5
背景介绍 This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
生物功能 Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. [UniProt]
细胞定位 Cell membrane. [UniProt]
预测分子量 23 kDa
翻译后修饰 The extracellular domain is cleaved and released from the cell membrane.

N-Glycosylated. [UniProt]

检测图片 (2) Click the Picture to Zoom In

  • ARG43767 anti-FNDC5 antibody WB image

    Western blot: HeLa and 3T3 cell lysate stained with ARG43767 anti-FNDC5 antibody at 1:1000 dilution.

  • ARG43767 anti-FNDC5 antibody WB image

    Western blot: C6 cell lysate stained with ARG43767 anti-FNDC5 antibody at 1:800 dilution.