ARG67025
anti-FOX3 / NeuN antibody [SQab30325]
anti-FOX3 / NeuN antibody [SQab30325] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant rabbit Monoclonal antibody [SQab30325] FOX3 / NeuN |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30325 |
| 同位型 | IgG |
| 靶点名称 | FOX3 / NeuN |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human NeuN |
| 偶联标记 | Un-conjugated |
| Protein Full name | RNA binding protein fox-1 homolog 3 |
| 別名 | RBFOX3, RNA Binding Fox-1 Homolog 3, HRNBP3, FOX-3, Hexaribonucleotide Binding Protein 3, RNA Binding Protein, Fox-1 Homolog 3, RNA Binding Protein Fox-1 Homolog 3, Neuronal Nuclei Antigen, Fox-1 Homolog C, NeuN Antigen, NeuN, RNA Binding Protein, Fox-1 Homolog (C. Elegans) 3, Neuronal Nuclei, FOX3, NEUN |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Human brain tissue |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # A6NFN3 Human RNA binding protein fox-1 homolog 3 |
|---|---|
| 基因名称 | RBFOX3 |
| 全名 | RNA Binding Fox-1 Homolog 3 |
| 背景介绍 | This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017] |
| 生物功能 | Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). [UniProt] |
| 细胞定位 | Cytoplasm, Nucleus |
| 预测分子量 | 34 kDa |
| 翻译后修饰 | Methylation [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67025 anti-NeuN antibody [SQab30325] IHC-P image.
Immunohistochemistry: Formalin-fixed and paraffin-embedded human brain tissue stained with ARG67025 anti-NeuN antibody [SQab30325].
Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0.
