ARG66792
anti-FPR2 / FPRL1 antibody
anti-FPR2 / FPRL1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FPR2 / FPRL1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FPR2 / FPRL1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide between aa. 130-210 of Human FPR2 / FPRL1. |
| 偶联标记 | Un-conjugated |
| 別名 | FMLP-related receptor I; N-formyl peptide receptor 2; RFP; FPRL1; Lipoxin A4 receptor; FPRH1; ALXR; FPRH2; HM63; FMLP-R-I; FPR2A; LXA4 receptor; FMLPX; Formyl peptide receptor-like 1; LXA4R; FMLP-R-II |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | SW480 | ||||
| 实际分子量 | ~ 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FPR2 |
| 全名 | formyl peptide receptor 2 |
| 生物功能 | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1374236). The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66792 anti-FPR2 / FPRL1 antibody WB image
Western blot: SW480 cell lysate stained with ARG66792 anti-FPR2 / FPRL1 antibody at 1:1000 dilution, overnight at 4°C.
